The state of similarity between tissues of the donor and the patient (recipient). The level of histocompatability describes how well a patient and donor are matched. The major histocompatability determinants in humans are called human leukocyte antigens ( HLA). The closer the match, the less likely the donated stem cells and the patient's body will react against each other (see GVHD.) HLA: See Human Leukocyte Antigens
literally means the ability of cells to get along with each other. Used to determine whether a transplanted tissue or organ will be acceptable by the recipient. Histocompatibility is determined by the major histocompatibility complex molecules.
The ability to accept grafts between individuals.
a term that reflects the similarity in the tissues of the donor and recipient. This similarity will help reduce the chances of rejection of the transplanted kidney. HLA (human leukocyte antigens) system - a genetically determined series of markers (antigens) present on human white blood cells (leukocytes) and on tissues that are important in histocompatibility
The ability of a host to tolerate a tissue graft.
condition in which the cells of one tissue can survive in the presence of cells of another tissue; "a successful graft or translplant requires a high degree of histocompatibility"
This is a term used to determine how identical two unrelated individuals are. Identical twins are totally histocompatible (same tissues). Brothers and Sisters are semi-histocompatible. The chances of unrelated individuals being histocompatible, like identical twins is one in 3 million.
The degree to which tissue from one organism will be tolerated by the immune system of another organism.
Referring to the similarity of tissue between different individuals. The level of histocompatibility describes how well the patient and donor are matched. The major histocompatibility determinants are the human leukocyte antigens (HLA). HLA typing is performed between the potential marrow donor and the potential transplant recipient to determine how close a HLA match the two are. The closer the match, the less the donated marrow and the patient's body will react against each other.
immunologic identity or similarity. Histocompatibility testing compares the HLA (also called MHC) "self" antigen markers of a tissue donor and recipient to determine whether a transplant is possible; a close match implies that the donor and recipient share the same MHC genes, reducing the chance that the transplant will be rejected. See also major histocompatibility complex.
A system that determines how closely the patient and donor blood stem cells match.
The degree of tissue similarity between the donor and recipient that will determine how easily the donor cells will be accepted and/or the likelihood and severity of graft-versus-host disease (GVHD).
Literally, the ability of tissues to get along; in immunology, it means identity in all transplantation antigens. These antigens, in turn, are collectively referred to as histocompatibility antigens.
The examination of human leukocyte antigens (HLA) in a patient, often referred to as "tissue typing" or "genetic matching." Tissue typing is routinely performed for all donors and recipients.
compatibility between two organs or tissues so that a graft (of an organ or of cells) is not rejected. This compatibility depends on the genetic similarities between donor and recipient.
Antigenic similarity of donor and recipient in organ transplantation.
Histocompatibility is the property of having the same, or mostly the same, alleles of a set of genes called the major histocompatibility complex. These genes are expressed in most tissues as antigens, to which the immune system makes antibodies. The immune system at first makes antibodies to all sorts of antigens, including those it has never been exposed to, but stops making them to antigens present in the body.
