(Judaism) sanctuary comprised of the innermost chamber of the Tabernacle in the temple of Solomon where the Ark of the Covenant was kept

Inside the Temple of Jerusalem was a room that was so holy that it was entered only one time during the whole year, on Yom Kippur, and only by the High Priest (Cohen Gadol). Inside the Holy of Holies, the High Priest would light a bowl of fragrant incense and pray for forgiveness.

A Holy of Holies is the most sacred place within a sacred building. In Judaism, it refers to the inner sanctuary of the Tabernacle and later the Temple in Jerusalem which could be entered by the High Priest only on Yom Kippur. Holy of Holies are also found within Egyptian Architecture, as well as within temples and churches of other faiths and traditions, to include the Ethiopian Orthodox Church, the Latter-day Saints, and Hinduism.

The Salt Lake Temple of The Church of Jesus Christ of Latter-day Saints contains a Holy of Holies wherein the Church's President—acting as the Presiding High Priest—enters to fulfill the relationship between the High Priest of Israel and God, in accordance with the LDS interpretation of the Book of Exodus .Buerger, David John. http://www.signaturebooks.com/excerpts/mystery.htm The Mysteries of Godliness. Signature Books (November 2002). Last accessed 2006-11-16 (excerpts only online).