a drug (e.g., nevirapine, delavirdine) that inhibits the action of the HIV-1 reverse transcriptase enzyme, thus blocking HIV replication, yet works in a different way than nucleoside analog drugs, by binding with the RT enzyme.
an antiviral drug used against HIV; binds directly to reverse transcriptase and prevents RNA conversion to DNA; often used in combination with other drugs
A substance/drug (e.g., nevirapine), not like an RNA or DNA building block, which nevertheless inhibits the reverse transcriptase enzyme and interferes with viral replication.
a member of a class of compounds, including DELAVIRDINE, NEVIRAPINE and EFAVIRENZ, that acts to directly combine with and block the action of HIV's REVERSE TRANSCRIPTASE enzyme. In contrast, NUCLEOSIDE ANALOGS block reverse transcriptase by capping the unfinished DNA chain that the ENZYME is constructing.
a drug (e.g., nevirapine, delavirdine, efavirenz) that binds with and inhibits the action of the HIV reverse transcriptase enzyme, thus blocking viral transcription and replication.
A type of antiretroviral drug designed to block the reverse transcriptase enzyme, but not of a nucleoside chemical structure. [example: Sustiva(tm) (efavirenz) EFV
A class of antiretroviral drug that inhibits the action of reverse transcriptase, one of the enzymes HIV needs to make copies of itself. Unlike another class of drug called NRTIs, NNRTIs are not effective against the type of HIV known as HIV-2.