the development of resistance to one agent (e.g., drug) which also confers resistance to another (often similar) agent.
resistance of HIV to two or more drugs.
Resistance of a virus to more than one drug of the same class, e.g. HIV resistance to certain protease inhibitors may result in a PWA being unable to benefit from other protease inhibitors. HIV resistance to any one of the three current non-nucleoside RT inhibitors has been shown to rule out the clinical use of any of the others in most cases.
The phenomenon in which a microbe that has acquired resistance to one drug through direct exposure, also turns out to have resistance to one or more other drugs to which it has not been exposed. Cross-resistance arises because the biological mechanism of resistance to several drugs is the same and arises through the identical genetic mutations.
Occurs when one HIV med causes resistance to one or more of the other HIV meds in the same class ("family") of drugs, even if the person hasn't yet taken it. When one HIV med can no longer recognize HIV and attack it, other HIV meds that work almost the same way may not be able to recognize and target the virus either.
resistance selected by one drug which, in turn, confers resistance to one or more drugs not included in the current treatment
the development of resistance to one agent (e.g., a drug) which also confers resistance to another agent (e.g., a similar drug of the same class).
The phenomenon by which HIV and other disease-causing organisms become resistant to more than one drug after a single therapy. For example, people who develop resistance from taking one non-nucleoside reverse transcriptase inhibitor (NNRTI) are likely to be cross-resistant to other drugs in the same class.
Refers to the phenomenon in which a microorganism that has acquired resistance to one drug through direct exposure has also developed resistance to one or more other drugs to which it has never been exposed. Cross-resistance arises because the mechanism of resistance to several drugs is the same and is due to identical genetic mutations.