refers to the property of being biologically compatible by not producing a toxic, injurious, or immunological response or rejection in living tissue. Unknowns in the bodily response is a principle concern when using artificial materials in the body and hence the biocompatibility of a material is an important design consideration in such materials
Characteristics of some materials.
Referring to the degree of tissue or systemic reaction caused by a foreign material in the body.
Defines the materials used in a system (i.e. fittings, tubing, and valves) that do not change the bioactivity of the biological substances that come into contact with the surface of these materials. (Note that in chromatographic systems, the tubing and column contribute over 99% of the surface area and the valves and fittings are insignificant.)
A characteristic of some materials that when they are inserted into the body do not produce a significant rejection or immune response.
The ability of a biomaterial to perform with an appropriate host response in a specific application Biomaterial: A material intended to interface with biological systems to evaluate, treat, augment or replace any tissue, organ or function of the body
The quality of not having toxic or injurious effects on biological function
Compatibility with living tissue or a living system by not being toxic or injurious.
General expression for the suitability of a material for use in the human body and in the endogenous fluids. For NiTinol, a multitude of clinical studies and long clinical history have shown that the biocompatibility is excellent, especially in terms of cytocompatibility, haemocompatibility, genocompatibility, and corrosion performance. The most current studies report that the overall biocompatibility of NiTi alloys is comparable to stainless steel and Titanium alloys. In some applications, such as stents, recent studies suggest that the biocompatibility of NiTi alloys may be even superior to stainless steel.
Biocompatibility is the ability of a material to perform with an appropriate host response in a specific application. (Williams, 1999) The critique against this definition usually boils down to the fact that it is not possible to make a single test that determines whether a material is biocompatible or not. Indeed, since the hemostasis of the immune response and repair functions in the body are so complicated it would seem odd that one can make one test to determine the biocompatibility of any given material.
