Definitions for "ENDOTOXIN"
Related Terms:
Endotoxins, Exotoxin, Pyrogen, Bacterial toxin, Enterotoxin, Lipopolysaccharide, Toxins, Toxin, Bactericidal, Antibiotic, Bacteriostat, Lysozyme, Pyrogenic, Immune system, Antitoxin, Killed vaccine, Bacterin, Antiseptic, Antimicrobial, Co-receptor, Bacteriostatic, E.coli, Cytotoxin, Inoculation, Germicidal, Cd4, Cd4 cells, Hypersensitive response, Germicide, Antiparasitic, Inoculate, Lysis, Bactericide, Ccr5, Antibiotics, Nk cells, Food poisoning, Antibacterial, Interferon, Complement system, Cytotoxic, T4 cell, Cell-mediated immunity, Biological agent, Chemokines, Cd4 cell, Vaccine, Cytotoxic t lymphocyte, Dendritic cells
A biological agent that is part of the outer membrane of some bacteria. Endotoxins are highly toxic, capable of causing fever, malaise, respiratory distress, even death.
Substance containing lipopolysaccharide complexes found in the cell wall of bacteria, principally gram-negative bacteria; felt to play an important role in many of the complications of sepsis such as shock, DIC, and thrombocytopenia.
The lioppolysaccharide associated with the outer membrane of Gram-negative bacteria.
The lipopolysaccharide of the outer membrane of Gram-negative bacteria, extractable from cells with trichloroacetic acid but not naturally released in quantity until cell lysis. The lipid A portion of the lipopolysaccharide is responsible for its toxic effects, which include leukopenia, thrombocytopenia, fever, and shock. Unlike the specific exotoxins, endotoxins from various organisms have similar pathogenic effects. Also known as bacterial pyrogen.
a lipopolysaccharide component of the membrane of gram-negative bacteria that is heat stable and toxic; a secreted toxin produced by bacteria is termed an "exotoxin"
A lipopolysaccharide (LPS) derived from the outer membrane of gram-negative bacteria. Endotoxins greatly stimulate the immune system in a non-specific manner leading to endotoxic shock, in which high fever, hypertension and death may occur.
Toxin in the cell walls of all gram negative bacteria.
A type of bacterial toxin having the following properties: Produced only by gram-negative bacteria Endotoxins are a component of the gram-negative cell wall The action of endotoxin requires the presence of the bacteria in the host. The endotoxin may be released from the cell wall as the cells die and disintegrate Endotoxin is composed of Lipid A: Part of the lipopolysaccharide layer Endotoxin is heat-resistant Mode of action: Irritation/inflammation of epithelium, GI irritation, capillary/blood vessel inflammation, hemorrhaging
a heat stable toxin (often a lipid-polysaccharide-polypeptide complex) present in the cell wall of microorganisms and released by the death of the organism that produced it; endotoxins are pyrogenic and increase capillary permeability.
Microbial toxin, such as a cell-surface polysaccharide, that is not easily separated from the cell.
A toxin produced by bacteria which causes illness.
a toxin that is confined inside the microorganisms and is released only when the microorganisms are broken down or die
a poison found in the cell membrane of some gram-negative bacteria, which is released when the cell is damaged or destroyed
a poisonous substance that is released from bacteria after the bacteria die or break apart
Any of a class of lipids found in the outer membranes of gram-negative bacteria; in people, the toxins cause diarrhea and/or septic shock.
A highly toxic chemical component of the cell walls of bacteria that occur normally in the intestine. Endotoxin can be released into the bloodstream when the bacteria die.
A substance found in the cell walls of certain bacteria that can be extremely toxic to people, producing fever, shock, and even death.
the lipopolysccharide of gram negative bacteria, the toxic character of which reside in the lipid protein. Endotoxins can produce pyrogenic reactions in persons exposed to their bacterial component.
a heat-resistant pyrogen (specifically a lipopoly-saccharide) found in the all walls of certain pathogenic (disease-producing) bacteria
A toxic product of bacteria which is associated with the structure of the cell, and can only be obtained by destruction of the cell
A toxin produced by bacteria. The toxin is present in the :environment only after the death of the bacteria.
a heat-stable toxin associated with the outer membranes of certain gram-negative bacteria. Endotoxins are not secreted and are released only upon lysis of the cells. They are composed of complex lipopolysaccharide molecules. The polysaccharide unit (somatic O antigen) is responsible for antigenicity; the phospholipid moiety (lipid A) is the source of toxicity.
A toxin the originates inside the body. (For example, from certain by-products of digestion.)
see lipopolysaccharide.
A pyrogenic product (e.g., lipopolysaccharide) present in the bacterial cell wall. Endotoxin can lead to reactions in patients receiving injections ranging from fever to death.
A toxic substance that remains inside the organism (e.g., bacteria) that produces it. Endotoxins are cell wall components of Gram-negative bacteria and are inherently toxic and can lead to various problems, but this occurs mainly when they are present in very high concentrations or when the microorganisms that produce them are viable.
A heat resistant pyrogen, found in the cell walls of viable and nonviable bacteria. They are more stable than bacterial cells and are not destroyed at normal bacterial disinfecting temperatures (such as in autoclaving).
A poisonous substance produced by microorganisms that is not secreted into the surrounding medium but confined within the microbial cell.
(en - do - tok - sin) A large toxic molecule derived from the outer cell wall of Gram-negative bacteria. Endotoxin is a complex molecule of polysaccharide, lipid A, and other cell wall components.
A toxin produced by certain bacteria and released upon destruction of the bacterial cell
A toxin produced inside certain bacteria.
a component of the cell wall of gram-negative bacteria.
Part of the outer wall of a gram-negative bacteria. It can cause fever, changes in white blood cell counts, increased airway resistance, shock, and even death.
The lipopolysaccharide fragments of gram-negative bacterial cell walls having nominal molecular weights of a few thousand to one million; considered to be pyrogens as they may have a fever inducing effect.
A poison produced by Escherichia coli that causes systemic response (fever, diarrhea, inappetence) to coliform mastitis in cows.
Poison that hurts body tissues.
A toxin present inside a bacterial cell.
A bacterial toxin composed of protein, lipid, and polysaccharides.
A heat-resistant pyrogen (specifically a lipopolysaccharide) found in the cell walls of certain disease-producing bacteria.
Lipopolysaccharide produced by Gram-negative bacteria, which activates B cells and macrophages
Endotoxins are potentially toxic, natural compounds found inside pathogens such as bacteria. Classically, an "endotoxin" is a toxin, which unlike an "exotoxin", is not secreted in soluble form by live bacteria, but is a structural component in the bacteria which is released mainly when bacteria are lysed.