To communicate a disease to (a person) by inserting infectious matter in the skin or flesh, especially as a means of inducing immunological resistance to that or related diseases; as, to inoculate a person with the virus of smallpox, rabies, etc. See Vaccinate.
Fig.: To introduce into the mind; -- used especially of harmful ideas or principles; to imbue; as, to inoculate one with treason or infidelity.
To introduce microorganisms into (a growth medium), to cause the growth and multiplication of the microorganisms; as, to inoculate a fermentation vat with an actinomycete culture in order to produce streptomycin.