Tendency of an aging body to mistake its own tissues for foreign invaders and to attack and destroy these tissues.
The condition in which antibodies are produced against the bodies own tissues.
In immunology, the condition in which one's own tissues are subject to deleterious (in plain English, harmful) effects of the immune system, as in autoimmune disease. You could describe it this way: "To borrow a wartime analogy, autoimmune disorder is similar to the phenomenon of "friendly fire," whereby the defensive forces mistake the "self" for the "enemy" and attack the "self" with the same arsenal stored up to fight invaders."
A condition in which an individual's immune system starts reacting against his or her own tissues, causing diseases such as lupus.
The production of antibodies against the tissues of your own body
a state or disease in which the body's immune system attacks the body's own tissues.
A condition characterized by a specific antibody (antiphospholipid antibody or antibodies to DNA) or cells (such as Natural Killer Cells) which react with molecules or constituents of the body's own tissue and cause disease such as Rheumatoid arthritis and lupus.
A condition in which the immune system produces antibodies against the body's own proteins or tissues. This may result in an autoimmune disease such as lupus, type 1 diabetes, rheumatoid arthritis, or multiple sclerosis.
The condition in which antibodies are fighting against the body's own tissues.
A malfunction of the immune system in which one's own tissues or organs are not recognized as self and are attacked by the body's immune system
The body's tolerance of the antigens present on its own cells (i.e., self- or autoantigens). The most current theory of self-tolerance is that developing self-reactive T lymphocytes (those with receptors that react to self-antigens) are destroyed in the thymus by negative selection. Self-reactive T cells that escape destruction in the thymus may become tolerant because they are exposed to thousands of self-antigens as they circulate in the blood. The loss of self-tolerance is believed to occur when self-antigens are damaged, when they link with a foreign antigen, or when the structure of a self-antigen is very similar to that of a foreign antigen (molecular mimicry). The changes in the appearance of the self-antigen cause T-cell receptors to perceive them as foreign and stimulate B-cell production of autoantibodies that attack self-antigens, producing inflammation and cell destruction. SEE: antigen; autoantibody; autoimmune disease.
An abnormal state in which the immune system mistakenly attacks and destroys certain types of their own normal, healthy cells. In Type I diabetes, autoimmunity destroys the beta cells that produce insulin.
AW-toe-imm-YUN-i-tee An organism's immune system attacking its own body. 800
A condition in which the body's immune system mistakes its own cells for outside invaders and attacks them. Type 1 diabetes develops when the immune system attacks the insulin-producing beta cells of the pancreas, destroying them, and halting insulin production.
A condition by which the host immune system mounts a response against its own tissues or organs. Autoimmune responses typically lead to a wide array of medical conditions such as Type I (juveline) diabetes, rheumatoid arthritis, lupus erythematosus, etc...
A condition in which the body's immune system mistakenly fights and rejects the body's own tissues.
Autoimmunity is when the body's natural defences [the immune system] mistakenly attacks the body's own tissue. "Auto" is derived from the Greek auto, meaning self, and autoimmune means attacking self.
Response of the immune system against components (antigens) of the host itself (rather than against invading parasites, bacteria or viruses). This autoimmune attack is mediated by antibodies or hematopoietic cells (usually lymphocytes).
A condition in which the body mounts an immune response against one of its own organs or tissues.
Immunity Proteins Immunization Protozoan
A misdirected immune response that occurs when the immune system goes awry and attacks the body itself. See the entire definition of Autoimmunity
An inflammatory reaction to one's own tissues.
A condition in which the body's immune system produces antibodies in response to its own tissues or blood components instead of foreign particles or microorganisms.
in HIV vaccination, a theoretical adverse effect in which the vaccine causes immune responses that are inappropriately directed at a person's own tissues. B lymphocyte (B cell): one of the two major classes of lymphocytes, B lymphocytes are white blood cells of the immune system that are derived from the bone marrow and spleen. B cells develop into plasma cells, which produce antibodies.
when the immune system attacks healthy tissue, or "self"
Lethal Syphilis Lupus Systemic
Immune-mediated destruction of the body's own cells and tissues; immunity against self.
Insulin Reperfusion Interferons Rheumatoid
A condition characterised by an immune response against constituents of the body's own tissues
In case of autoimmunity something goes wrong with immunity: the body's own defence mechanism. Instead of directing its defence against foreign intruders (bacteria, viruses,..) it attacks its own body cells by producing large amounts of autoantibodies that cause inflammatory diseases or autoimmune diseases.
An immune response to "self" tissues or components. Such an immune response may have pathological consequences leading to autoimmune diseases.
an immune reaction against one's own tissues
Condition in which the immune system reacts against the body's own tissue
A condition in which the body's immune system malfunctions and attacks the body's own cells and tissues. It is the basis of the disease process in MS as well as other diseases.
The immune system’s sensitivity to normal cells and tissues, resulting in the production of autoantibodies.
Black's medical dictionary, G Macpherson ed; 38th ed A reaction to an individual's own tissues to which tolerance has been lost. Autoantibodies are not necessarily harmful and are commonly encountered in healthy persons.
Immune recognition and reaction against the individual's own tissue.
Autoimmunity is the failure of an organism to recognize its own constituent parts (down to the sub-molecular levels) as "self", which results in an immune response against its own cells and tissues. Any disease that results from such an aberrant immune response is termed an autoimmune disease. Prominent examples include diabetes mellitus type 1 (IDDM), systemic lupus erythematosus (SLE), Sjögren's syndrome, Hashimoto's thyroiditis, Graves' disease, and rheumatoid arthritis (RA).
