a vaccine made from an infectious agent that has been inactivated or killed in some way. See Killed Vaccine.
see "whole killed vaccine"
A vaccine in which the infectious agent has been modified in some way (most often chemically) so that it no longer can infect and replicate within the host, but nevertheless is still capable of stimulating an immune response.
These vaccines are manufactured either from the killed germ, or from the toxin, or using parts of the germ either as component vaccines or as conjugate vaccines.