Definitions for "Interferons"
Related Terms:
Interferon, Interleukin-1, Interleukin-2, Interleukins, Alpha interferon, Cell-mediated immunity, Immune system, Cell mediated immunity, Cellular immunity, Cytokines, Interleukin, Lymphokine, Suppressor t cells, Memory cell, Helper cell, Lymphokines, Humoral immunity, Superantigen, T lymphocyte, Cytotoxic t lymphocyte, Antibodies, Innate immunity, Cytokine, Antibody-dependent cell-mediated cytotoxicity, Helper t cell, Antibody, Memory cells, Ctl, Antigen-presenting cell, Antibody-mediated immunity, Monoclonal antibodies, Cytotoxic t cell, Nk cells, Opsonization, Immunomodulator, Complement, Immunoglobulins, Immune response, Natural killer cells, Immunocompetent, Cellular immune response, Helper t cells, Natural killer cell, Biologic response modifiers, Biologic therapy, Complement system, Biological response modifiers, Autoimmunity, Immunodeficiency, Antigen
A cytokine that interferes nonspecifically with the reproduction of viruses.
A group of naturally occurring proteins that act as chemical messengers between cells. Three have so far been discovered, alpha, beta and gamma, all of which have immune-modulating effects. Interferons are used in the treatment of cancer and autoimmune diseases, such as MS.
A family of disease-fighting molecules produced naturally in the body, but also made in the laboratory as drugs to enhance the body's ability to destroy viruses and cancer cells.
Proteins produced by the body with the specific purpose of regulating cell functions. Interferons are produced in the laboratory in large quantities, and are sometimes used in the treatment of certain cancers.
A specialized group of protein molecules capable of inhibiting virus replication and the growth of tumor cells, and of modulating the activities of certain components of the immune system.
A family of naturally-occurring proteins derived from human cells and involved principally in fighting viral infections. They are now available as products of genetic engineering for use in the treatment of leukemias, especially chronic myelogenous leukemia and in combination with other drugs some lymphomas.
Help shield cells from various viruses. They are produced naturally by the human body or in laboratories for use in drugs.
Peptides released by virus-infected cells, especially lymphocytes, that slow viral replication and make other cells more resistant to viral infection.
Glycoproteins released by cells to stimulate immune responses following invasion by viral or other infectious agents
A protein released by cells in response to viral infection; activates the synthesis and secretion of antiviral proteins.
IFNs) Small group of cytokines that bind to cell- surface receptors on target cells inducing changes in gene expression leading to an antiviral state or other cellular responses important in the immune response.
A group of proteins that increase the resistance of cells to viral infection. Interferons also act as cytokines and can enhance some immune responses.
A group of molecules involved in signalling between cells of the immune system, and in protection against viral infections.
Immune system proteins that are grouped into three main types: alpha(a), beta(ъ) and gamma(γ). Alpha and beta interferons mainly work to suppress viral infections. Gamma interferon works on other infectious agents as well as cancer cells. Alpha and beta interferons probably alter or lessen the immune system damage to the myelin, but it is not known. In treatment of MS, they make attacks less frequent and severe and may affect the progress of the disease. Drugs approved for use in the United States are interferon beta 1-a (Avonex, Rebif) and interferon beta 1-b (Betaseron).
Cytokines that help cells to fight viruses. Alpha interferon and beta interferon are made by white blood cells, fibroblasts and other cells. (Manufactured versions are useful as MS treatments.) Gamma interferon is produced by inflammatory T cells and natural killer cells and its main action is to trigger macrophages to help fight infection. Gamma interferon makes MS worse.
Proteins formed when cells are exposed to a virus or another particle of nucleic acid. Interferons can be used therapeutically for certain diseases such as psoriasis.
a family of proteins naturally produced in the body that play a role in controlling the immune system. One type of interferon, interferon beta is used in MS as a disease modifying therapy.
A cytokine that interferes non-specifically with the reproduction of viruses.
cytokines belonging to a family of antiviral proteins that occur naturally in the body. Gamma interferon is produced by immune system cells, enhances T-cell recognition of antigens and causes worsening of MS symptoms. Alpha and beta interferon probably exert a suppressive effect on the immune system and may be beneficial in the treatment of MS.
Proteins released by cells in response to viral infection; activate the synthesis and secretion of antiviral proteins.
Proteins produced by human cells which ward off viral infection by “interfering” with viral growth. Interferons play an important role in the body's immune defenses.
A group of proteins which are made by cells when infected with a virus, and which can prevent nearby cells from being infected. Different interferons are being tested for there
(in-ter-FEER-ons): Biological response modifiers (substances that can improve the body's natural response to disease). Interferons interfere with the division of cancer cells and thus slow the growth of the tumor. There are several types of interferons, including interferon alfa, beta, and gamma. These substances are normally produced by the body. They are also made in the laboratory for use in treating cancer and other diseases.
Substances that interfere with the ability of viruses to reproduce.
Proteins produced naturally by white blood cells that stimulate the growth of certain disease-fighting blood cells in the immune system. Manufactured forms of interferons are used in cancer immunotherapy to improve the body's natural response to disease.
Natural proteins produced by the normal cells of most body tissues in response to viral infections and disease, including cancer. Interferons affect immune responses and boost resistance to viral infection. Interferon therapies have been shown to help the body's immune system fight disease more effectively and may inhibit the growth of blood vessels that feed cancer cells.
A group of proteins called cytokines produced by white blood cells, fibroblasts, or T-cells as part of an immune response to a viral infection or other immune trigger. The name comes from the proteins' ability to interfere with the production of new virus particles. Source: http://health.enotes.com/neurological-disorders-encyclopedia/interferons
Proteins that strengthen the immune system. Interferon-alfa helps fight cancer cells.
Messenger substances, with which the body's own defence cells communicate with one another. Today, these substances can be produced artificially and are used in the treatment of various forms of cancer.