"Live Wire" is a song by Australian hard rock band AC/DC. It is the fourth track of their Australian album T.N.T., released in December 1975 (see 1975 in music), and was written by Angus Young, Malcolm Young, and Bon Scott.

"Live Wire" is a 1964 soul single released by Motown girl group Martha and the Vandellas. The song was produced by Holland-Dozier-Holland under the same format of their earlier hit singles "(Love is Like a) Heat Wave" and "Quicksand". The song explained why the narrator can't come up with words to tell her lover that she was through with him because when she looks at him, she feels that he is "like a bolt of lightning" and that he's a "live wire".

Live Wire is a fictional character in the Marvel Universe.