A group of antidepressant drugs that prevent the enzyme monoamine oxidase from deactivating neurotransmitters of the central nervous system.
The first class of antidepressant medications, such as Nardil and Parnate. They are effective, especially for some kinds of depressions, but they impose difficult dietary restrictions on patients and have been largely superseded by the selective serotonin reuptake inhibitors (SSRIs).
drugs which enhance the effect of certain chemical transmitters like dopamine, by inhibiting the function of enzymes that oxidize them (break them down).
The first class of antidepressants. MAOIs prevent the metabolism of the brain chemicals serotonin and norepinephrine by inhibiting the enzyme monoamine oxidase, making these chemicals more available for normal brain function.
An older class of antidepressant medications that work through inhibition of the enzyme (monoamine oxidase) that breaks down certain naturally occurring CNS neurotransmitters (the amines), including epinephrine, serotonin, and norepinephrine, thereby resulting in increased availability of these neurotransmitters and associated improvement in depressed mood. MAOIs in current use in Western psychiatry include isocarboxizide (Marplan), phenelzine (Nardil), and tranylcypromine (Parnate).
Enzyme responsible for breaking down monoamines, resulting in decreased availability of the neurotransmitters; drugs that inhibit MAO are typically prescribed as antidepressants.
Drugs used in the treatment of depression that are thought to work by stopping an enzyme that breaks down certain chemicals in the brain.
A type of drug which falls into two types - Type A (drugs like isocarboxazid (Marplan); phenelzine (Nardil); tranylcypromine (Parnate)) which are used to treat depression and anxiety. Due to their potential interactions with other drugs, they are not usually suitable for people with Parkinson's. Type B drugs include selegiline hydrochloride (Elderpryl or Zelapar) which is used to treat Parkinson's. See the PDS information sheet Depression and Parkinson's (FS56) - 603kb pdf format and the booklet, The Drug Treatment of Parkinson's Disease (B13).
MAOIs are anti-depressants that work by blocking the action of a chemical substance called monoamine oxidase (MAO) in the nervous system. They are sometimes used when people with depression do not respond to other types of anti-depressants. Medications in this group include phenelzine (Nardil), tranylcypromine (Parnate) and isocarboxazid (Marplan).
antidepressants that stop MAO from breaking down neurotransmitters, which effectively makes more of those neurotransmitters available to the brain.
a class of drugs used to treat depression. They also help treat headaches. People taking MAO inhibitors must be careful not to eat foods containing tyramine, as this can cause increased blood pressure.
MAO-I) Drugs (e.g. selegiline) that block monoamine oxidases resulting in prolonged availability of dopamine in the brain
Monoamine oxidase inhibitors (MAOIs) prevent the metabolism of the brain chemicals serotonin and norepinephrine by inhibiting the enzyme monoamine oxidase, making these chemicals more available for normal brain function.
Drugs that enhance the effect of dopamine by preventing enzymes from breaking them down
A group of medicines sometimes prescribed to treat severe depression. MAOIs increase the concentration of chemicals responsible for transmitting information between nerves in particular regions of the brain, which may lead to increased mental functioning.
Drugs used in the treatment of clinical depression. They block an enzyme that breaks down neurotransmitter chemicals in the brain.
Antidepressant medications that act by preventing the breakdown of the monoamines serotonin and norepinephrine (see Depression).
