A muscle which directly engages in an action around a joint which has another muscle that can provide an opposing action (antagonist).
A molecule that produces the same or elevated effect as a natural substrate or effector molecule.
Any drug that enhances the actions of a specific neurotransmitter. go to glossary index
In receptor-ligand interactions, an agonist is a molecule that binds receptor and fully induces post-receptor signalling events. The opposite of antagonist.
Any molecule that improves the activity of a different molecule; e.g., a hormone, which acts as an agonist when it binds to its receptor, thus triggering a biochemical response.
a molecule or drug which combines with a receptor and produces a biological response.
A drug or other chemical that can combine with a receptor on a cell to produce a physiologic reaction typical of a naturally occurring substance
A chemical entity that is not naturally occuring within the body which acts on a family of receptors (such as mu, delta, and kappa opiate receptors) in such a fashion that it is an agonist or partial agonist on one type of receptor while at the same time it is also an antagonist on another different receptor.
A chemical substance capable of combining with a receptor on a cell and initiating a reaction or activity
A molecule that triggers a cellular response by interacting with a receptor.
a pharmacological term referring to a substance that activates membrane receptors, producing a cellular response.
Party of the agon. Agonists are usually available in two flavors protAGONIST and antAGONIST. One of each is recommended. However, the chief conflict of the story is not necessarily between the good guy and the bad guy. The conflict may pit your protagonist against nature or adverse circumstances or between conflicting impulses or values within him- or herself.
a drug capable of combining with receptors to initiate an action that can be known in advance.
Substance which binds to cell receptors normally responding to naturally occurring substances and which produces a response of its own. AN antagonist.
A muscle that relaxes and stretches so that a muscle or muscle group on the opposite side of the joint can contract.
refers either to: (i) an agent that binds and activates a membrane receptor, and which in some cases defines that receptor type, e.g. the N-methyl-d-aspartate (NMDA) glutamate receptor; or (ii) a muscle that acts in a similar fashion to that performing the primary movement around a joint
A drug that 'mimics' naturally occurring chemicals which stimulate receptors in the brain and CNS periphery (endogenous agonists). Agonists bind to and activate receptor sites. Their effect depends upon the drug's affinity for the receptor site and its concentration at the site. See also antagonist, pharmacotherapies
a compound that acts on the same receptor, and with a similar effect, as the natural ligand.
a muscle whose contraction opposes the action of another muscle, its antagonist, which at the same time relaxes
A chemical or drug that mimics neurotransmitter activity.
someone involved in a contest or battle (as in an agon)
a muscle that contracts while another relaxes; "when bending the elbow the biceps are the agonist"
(biochemistry) a drug that can combine with a receptor on a cell to produce a physiological reaction
a drug that causes a response
a drug that stimulates activity at cell receptors that are normally stimulated by such naturally occurring substances as melatonin
a ligand that binds to a receptor and produces a biological effect (direct acting) or a compound that indirectly produces the same effect of a neurotransmitter (indirect acting)
a ligand that binds to the active site of a receptor and initiates some change in body function
an endogenous substance or a drug that can interact with a receptor and initiate a physiological or a pharmacological response characteristic of that receptor (contraction, relaxation, secretion, enzyme activation, etc
a substance or drug that can interact with a receptor and initiate a characteristic physiological or pharmacological response
a substance that attaches to nerve cell receptors and imitates an existing neurochemical
a substance that binds to a receptor and triggers a response by the cell
a substance that binds to the receptor and produces a response that is similar in effect to the natural ligand
a substance that can bind to a receptor on a cell in such a way as to produce a physiological reaction similar to that of the naturally occurring substance for which the receptor is specific
a substance that can set a process into motion
a substance which binds to the receptor and activates it
a substance that imitates the effect of the natural nerve-mediator, for example, GABA
a compound that will bind to a receptor to form a complex which elicits a full pharmacological response, peculiar to the nature of the receptor involved.
A drug which binds to a receptor and activates it, producing a pharmacological response (e.g. contraction, relaxation, secretion, enzyme activation, etc.).
The muscle or muscles that are doing the work to move bones in a specific motion that are coordinated with the antagonist(s), which perform the opposite motion. The agonists and antagonists are coordinated in the sense that the antagonist decelerates or controls agonist action. Also sensors in agonists and antagonists feedback information to the nervous system that helps control speed, force of contraction and flexibility of the muscles. When this coordinated system is well-trained and functioning well, performance is enhanced and injuries, such as muscle strains are prevented.
When talking about drugs, this refers to a compound that stimulates or enhances activity of the cell receptors.
A drug capable of combining with receptors to initiate drug actions; it possesses affinity and intrinsic activity.
Muscles directly engaged in contraction as related to muscles that relax at the same time.
A muscle in a state of contraction, with reference to its opposing muscle, or antagonist.
A drug that imitates a neurotransmitter. Dopamine agonists are drugs that imitate the actions of dopamine.
A chemical that mimics or copies the actions of another chemical. IMITREX is believed to mimic some of the actions of serotonin.
A molecule that activates a cell receptor.
a drug that binds to receptors, stimulating their function
A substance that blocks the action of another.
A muscle that is contracting to create joint movement.
A molecule that activates a receptor. See Antagonist.
A substance which interacts with a receptor to cause a biological response.
A drug that increases neurotransmitter activity by directly stimulating the nerve cell receptors.
a drug that increases neurotransmitter activity by stimulating the dopamine receptors directly.
A chemically simple, but psychoactively complex drug commonly used in many beverages. Alcohol is a depressant drug with significant liability for abuse and addiction.
A substance that mimics the actions of a specific neurotransmitter or hormone by binding to the specific receptor of the naturally occurring substance. Drugs are often designed as receptor agonists to treat a variety of diseases and disorders when the original chemical substance is missing or depleted.
A contracting muscle that is resisted or counteracted by another muscle, the antagonist.
Activator; an agonist at a given neuroreceptor activates that receptor.
Greek agonistes = rival, hence, a muscle in apparent contest with another. Used for a prime mover.
a chemical or drug that enhances the activity of a neurotransmitter such as dopamine
an agent that binds to a receptor on a cell's surface and promotes a specific cellular activity. Agonists often exert their effect by mimicking the activity of the body's natural neurotransmitters and other regulatory chemicals or of other drugs. Also refers to a drug or substance that promotes the activity of another drug. Contrast with antagonist.
A substance that acts on receptor sites to produce certain responses.
A chemical or drug that mimics the action of a neurotransmitter by stimulating the target site or receptor
A molecule capable of combining with a biochemical receptor on a cell and initiating the same response as occurs naturally
a class of medication, which stimulates the dopamine receptors directly.
In pharmacology, a drug that has affinity for and stimulates physiologic activity at cell receptors normally stimulated by naturally occurring substances.
A neurotransmitter, a drug or other molecule that stimulates receptors to produce a desired reaction.
a chemical substance such as a drug capable of combining with a cellular receptor and initiating an action; an antagonist combines with the receptor, but does not initiate the action
a substance that mimics the effects of a natural compound (such as a hormone or neurotransmitter) by binding to and activating the same cell surface receptor.
A molecule, such as dopamine, which activates a receptor, such as the dopamine receptor. Amino acid - These are the the building blocks of proteins, which are long chains of amino acids joined head to tail by what is called a peptide bond. Chemically, an amino acid consists of a single central carbon atom joined to four other items: an amino group (H3N) which acts as an acid; a carboxyl group (COO) which acts as a base; a hydrogen atom; and a variable side chain (R). There are 20 standard amino acids which form all of the proteins which occur in all living things: Lysine, Arginine, Histidine, Aspartic Acid, Glutamic acid, Asparagine, Glutamine, Serine, Threonine, Tyrosine, Glycine, Alanine, Valine, Leucine, Isoleucine, Proline, Phenylalanine, Methionine, Tryptophan, and Cystein.
The muscle that is the prime mover in a specific movement; also a chemical or drug that assists in initiating another drug's action.
A muscle responsible for producing a specific movement through concentric muscle action.
A substance which mimicks physiologic activity of the brain's natural neurotransmitters at cell receptors
An agonist muscle is one that is actively contracting; it is the muscle that is responsible for moving the body part.
A chemical substance that combines with a receptor on a cell and initiates an activity or reaction. See LHRH analogs.
A drug that combines with receptors to initiate drug actions.
Muscle directly engaged in contraction that is primarily responsible for movement of a body part.
A prime-mover muscle that is engaged in contraction and opposes the action of an antagonist muscle.
Chemical that acts like a neurotransmitter; increases the effect of a neurotransmitter.
a drug that effectively mimics the action of a natural chemical messenger within the body
A chemical that produces a response, such as excitation or inhibition of action potentials when it binds to a specific receptor. Opiates, cannabis, nicotine, and some hallucinogens are agonists.
A chemical compound that mimics the action of a natural neurotransmitter.
A chemical substance that simulates the action of a drug or a substance occurring naturally in the body.
a drug that shows an affinity for and stimulates a receptor.
Chemical messenger that binds to receptor and triggers cell's response; often refers to drug that mimics action of chemical normally in the body.
The muscle directly engaged in contraction.