An alkaloid found in the Calabar bean (the seed of Physostigma venenosum), and extracted as a white, tasteless, substance, amorphous or crystalline; -- formerly called eserine, with which it was regarded as identical.
A reversible anticholinesterase permitting an accumulation of acetylcholine (cholinergic). It readily crosses the blood-brain barrier. It improves the tone and action of skeletal muscles, increases intestinal peristalsis, acts as a miotic in the eye, and is used in treatment of BZ.
used in treatment of Alzheimer's disease and glaucoma