The reaction of a molecule with the solvent molecules when it enters a solution.
a chemical process in which solvent molecules and molecules or ions of the solute combine to form a compound
occurs at the mouth of the pore. During ion permeation, where ion is partially or fully dehydrated and therefore stabilized by interactions with the pore wall.
Ions in solution are normally combined with at least one molecule of solvent. This phenomenon is termed solvation.
Solvation is the attraction and association of molecules of a solvent with molecules or ions of a solute. As ions dissolve in a solvent they spread out and become surrounded by solvent molecules. The bigger the ion, the more solvent molecules are able to surround it and the more it becomes solvated.