This is when the body has become quite resistant to insulin. People can be genetically predisposed to insulin resistance, but can also become insulin resistant due to gaining weight, lack of physical activity and increasing age.

Insulin resistance is a condition in which cells no longer respond to normal insulin levels. The result is the body keeps releasing more and more insulin into the bloodstream in an attempt to maintain normal blood sugar levels. Saturated fats and High-Glycemic carbs are thought to cause Insulin Resistance.

Resistance of the body cells to take in glucose in the presence of insulin.

Insulin resistance is usually either caused or aggravated by obesity, particularly abdominal obesity. Hence diet to promote the loss of excess weight, together with exercise to improve muscle metabolism and aid weight loss can improve insulin sensitivity. When diabetes is present, tight glucose control can also enhance insulin sensitivity. Drugs which specifically target insulin resistance are now becoming available, but it is not yet known whether decreasing insulin resistance will in itself slow or prevent the development of macrovascular disease.

if you are insulin resistant, your muscle and liver cells are not good at taking up glucose unless there's a lot of insulin about. Chances are you'll have very high insulin levels even long after a meal, as your body tries hard to metabolise the carbohydrate in the meal.

A condition in which an individual requires a high level of insulin in order to maintain a normal blood sugar.

a reduced sensitivity to insulin in the tissues. The tissues are resistant to the effects of insulin so the pancreas has to secrete more insulin.

A condition in which the body's cells do not respond adequately to the hormone insulin. It can lead to higher blood sugar (glucose) levels, increased insulin production by the pancreas, and possibly even to diabetes.

This is a phenomenon of poor response to insulin. If sufficient insulin is produced, the individual can maintain normal blood glucose levels, but if insulin secretion is insufficient, the result is Type 2 diabetes.

Many people with Type II diabetes do not respond to the action of insulin, thus glucose cannot be used for energy.

A condition in which the body is resistant against the effects of insulin.

The inability of cells in the body to make proper use of insulin, a hormone needed to process sugar (glucose) correctly. Insulin resistance can cause insulin levels and glucose levels to increase in the blood and may play a role in the development of lipodystrophy (See Lipodystrophy).

a reduced sensitivity to how insulin works in your body, which makes it harder to control the level of glucose.

when the body develops a resistance to the effects of insulin.

The body's inability to respond to and use the insulin it produces. Insulin resistance may be linked to obesity.

This condition occurs when the cells of the body do not respond as efficiently as necessary to insulin.

Insulin resistance is a state reached when the body does not properly respond to and process the insulin it releases. Insulin resistance causes the pancreas to overproduce insulin. According to Drs. Michael and Mary Eades of Protein Power, insulin resistance causes high blood pressure, elevated cholesterol levels, coronary artery disease (heart disease), obesity, Type II diabetes and a host of other diseases and disorders.

When insulin is blocked from doing its job. It can be caused by excess hormones made by the placenta. It's also linked to being overweight.

many people with noninsulin-dependent diabetes produce enough insulin, but their bodies do not respond to the action of insulin. This may happen because the person is overweight and has too many fat cells, which do not respond well to insulin. Also, as people age, their body cells lose some of the ability to respond to insulin

The diminished ability of cells to respond to the action of insulin in transporting glucose (sugar) from the bloodstream into muscle and other tissues. Insulin resistance typically develops with obesity and heralds the onset of type 2 diabetes. It is as if insulin is "knocking" on the door of muscle. The muscle hears the knock, opens up, and lets glucose in. But with insulin resistance, the muscle cannot hear the knocking of the insulin (the muscle is "resistant"). The pancreas makes more insulin, which increases insulin levels in the blood and causes a louder "knock." Eventually, the pancreas produces far more insulin than normal and the muscles continue to be resistant to the knock. As long as one can produce enough insulin to overcome this resistance, blood glucose levels remain normal. Once the pancreas is no longer able to keep up, blood glucose starts to rise, initially after meals, eventually even in the fasting state. Type 2 diabetes is now overt.

The main problem in type 2 diabetes. The pancreas produces insulin, but the cells do not respond to it properly -- they're resistant.

a condition in which the body does not respond to insulin properly. This is the most common cause of type 2 diabetes.

Insulin resistance occurs when the normal amount of insulin secreted by the pancreas is not able to remove glucose from the blood into the cells for use as energy or storage for future use.

a condition in which the body doesnâ€(tm)t respond properly to insulin and is often a precursor to diabetes.

When the pancreas is no longer able to meet the demand for insulin, or the body is not properly using the insulin produced. This results in high blood glucose levels, because the glucose has difficulty getting inside the bodyâ€(tm)s cells.

Many people with noninsulin-dependent diabetes produce enough insulin, but their bodies do not respond to the action of insulin. Because the person is overweight with too many fat cells, which do not respond well to insulin. As people age, their body cells lose some of the ability to respond to insulin. Insulin resistance is also linked to high blood pressure and high levels of fat in the blood. Another kind of insulin resistance may happen in some people who take insulin injections. They may have to take very high doses of insulin every day (200 units or more) to bring their blood glucose (sugar) down to the normal range. This is also called "insulin insensitivity.

A condition in which the body does not respond normally to the action of insulin. Many people with type 2 diabetes have insulin resistance.

A condition in which the blood glucose level remains higher than it should at an insulin dosage of 2 units/pound of body weight per day in cats.

This occurs when the body does not correctly respond to and process the insulin it releases. In this state the pancreas overproduces insulin causing high blood pressure, elevated cholesterol, heart disease, obesity, type II diabetes and other disorders.

Impaired insulin effectiveness in both glucose uptake at the cellular level and decreasing glucose production in the liver.

A condition in which the body is unable to respond to and use the insulin it produces. As a result, the pancreas secretes more insulin into the bloodstream in an effort to reduce blood glucose levels.

this occurs when there is a defect in the receptor that recognizes insulin (the hormone that regulates the way the body uses and stores glucose). More insulin is then required to exert an action.

A reduced ability of the body to respond to and use the insulin it produces. Insulin resistance may be linked to obesity, hypertension and high levels of fat in the blood.

decreased sensitivity to the action of insulin. Typically measured as the degree that glucose is cleared from the blood in response to a given amount of insulin.

A condition in which the body is unable to use available insulin effectively. Insulin resistance is a common side effect of highly active antiretroviral therapy (HAART).

A reduced sensitivity to insulinâ€(tm)s action; underlies type 2 diabetes and can contribute to hyperglycemia (see Diabetes).

A reduced sensitivity in the tissues of the body to the action of insulin, which is, importantly, to bring glucose into those tissues to be used as a source of energy. When insulin resistance, or reduced insulin sensitivity, exists, the body attempts to overcome this resistance by secreting more insulin from the pancreas. This compensatory state of hyperinsulinemia (high insulin levels in the blood) is felt to be a marker for the syndrome. The development of Type II, or non-insulin dependent, diabetes occurs when the pancreas fails to sustain this increased insulin secretion. It is not clear how insulin resistance contributes to the presence of high blood pressure, but it is clear that the high insulin levels resulting from insulin resistance contribute to abnormalities in blood lipids - cholesterol and triglycerides. The syndrome is typically characterized by varying degrees of glucose intolerance, abnormal cholesterol and/or triglyceride levels, high blood pressure, and upper body obesity, all independent risk factors for cardiac disease.

A defect present in the majority of individuals with impaired glucose tolerance and essentially in all patients with Type 2 diabetes and is an impairment of insulin action.

Insulin resistance is the condition in which normal amounts of insulin are inadequate to produce a normal insulin response from fat, muscle and liver cells. Insulin resistance in fat cells results in hydrolysis of stored triglycerides, which elevates free fatty acids in the blood plasma. Insulin resistance in muscle reduces glucose uptake whereas insulin resistance in liver reduces glucose storage, with both effects serving to elevate blood glucose.