A star sapphire is a sapphire that exhibits an asterism in the form of a colorless, six-rayed star that reflects light. Star sapphires are cabochon cut. Laboratory-produced star sapphires ("Linde stars") were developed in 1947 by the Linde company; most star sapphires today are synthetic.

Star Sapphire is the name of several female supervillains in DC Comics, all connected in origin. For millions of years, an immortal race of warrior women, the Zamarons, had chosen physically identical mortals from across the cosmos to serve as host body for their Queen, whom they called Star Sapphire. She is then given the Queen's symbolic weapon, a crystal resembling an actual star sapphire which grants the user powers similar to the power ring of a Green Lantern.