Also called "clinical studies." Research studies with people. Each trial tries to answer specific scientific questions and to find better ways to prevent, detect, or treat diseases or to improve care.
Studies which compare a well-known, or standard, treatment with a newly developed treatment. Clinical trials are usually done in three phases. Phase I tests the safety of the treatment on a small number of patients. Phase II assesses the effectiveness of the treatment and usually involves a larger group of people. Phase III provides in-depth information about the effectiveness and safety, by comparing experimental treatment with the standard protocol. Phase III trials usually involve several thousand patients nationwide. Randomized clinical trials, considered the "gold standard" of scientific research, involve study participants who are randomly assigned to different treatment groups and then compared.
Medical research studies conducted on human subjects to answer scientific questions and to find better ways to prevent, detect or treat the disease.