A highly conserved sequence of 180 nucleotides common to many regulatory genes and coding for the DNA-binding part of the corresponding regulatory proteins. ~ See Also: Homeotic gene, Transcription factor.
A 180-base-pair sequence that is present in many developmental genes of animals and plants. It encodes a DNA-binding helix–turn–helix motif, indicating that homeobox-containing gene products function as transcription factors.
A DNA-binding motif found in many proteins involved in developmental regulation of gene expression.
Conserved DNA sequence that encodes a DNAbinding domain (homeodomain) in a class of transcription factors encoded by certain homeotic genes.
Conserved protein sequence which forms a DNA-binding domain (homeodomain) in a class of transcription factors encoded by certain homeotic genes.
Short (180 base pairs long) conserved DNA sequence that encodes a DNA-binding motif famous for its presence in genes that are involved in orchestrating the development of a wide range of organisms.
A 180-nucleotide sequence within a homeotic gene encoding the part of the protein that binds to the DNA of the genes regulated by the protein. homeosis Evolutionary alteration in the placement of different body parts. homeostasis(home-ee-oh- stay-sis) [Gk. homos, same or similar + stasis, standing] The steady-state physiological condition of the body.
A highly conserved region in a homeotic gene composed of 180 bases (60 amino acids) that specifies a protein domain (the homeodomain) that serves as a master genetic regulatory element in cell differentiation during development in species as diverse as worms, fruitflies, and humans.
A highly conserved nucleotide sequence that is important to the orchestration of gene expression during development.
one of various similar homeotic genes that are involved in bodily segmentation during embryonic development
a stretch of dna sequence found in genes involved in the regulation of the development (morphogenesis)
A DNA sequence found in several genes that are involved in the specification of organs in different body parts in animals; they are characteristic of genes that influence segmentation in animals. The homeobox corresponds to an amino acid sequence in the polypeptide encoded by these genes; this sequence is called the homeodomain.
A 180-base-pair segment of DNA found in a few genes (called Hox genes), perhaps regulating the expression of other genes and thus controlling large-scale developmental processes.
A short stretch of nucleotides whose base sequence is virtually identical in all the genes that contain it. It has been found in many organisms from fruit flies to human beings. In the fruit fly, a homeobox appears to determine when particular groups of genes are expressed during development.
A stretch of approximately 180 bp conserved in different homeotic genes.
A homeobox is a DNA sequence found within genes that are involved in the regulation of development (morphogenesis) of animals, fungi and plants. Genes that have a homeobox are called homeobox genes and form the homeobox gene family. They were discovered independently in 1983 by Walter Gehring and his colleagues at the University of Basel, Switzerland, and Matthew Scott and Amy Weiner, who were then working with Thomas Kaufman at Indiana University in Bloomington.