a vector used to clone DNA fragments from 300 kb to one megabase (unit of length for DNA fragments equal to one million nucleotides) in length. These clones can span large portions of the genome rapidly, but can be highly unstable
See Yeast artificial chromosome (YAC)
Yeast artificial chromosome, used as a vector system for cloning DNA fragments that can be hundreds of kilobases long. Linear cloning vectors constructed from essential elements of yeast chromosomes. They can accommodate foreign DNA inserts of 200 to 500 kb.
Yeast artificial chromosome. A cloning vector which contains sequences from a yeast chromosome required for DNA replication and segregration. Often used for cloning very large fragments of DNA.
Yeast artificial chromosome. A vector used to clone DNA fragments (up to 400 kb); it is constructed from the telomeric, centromeric, and replication origin sequences needed for replication in yeast cells. Compare cloning vector.
Yeast artifical chromosome. An artifical chromosome containing a yeast centromere, two telomeric sequences, and a marker. The YAC is constructed by cloning very large genomic fragments (up to one million bases) from another species into yeast vectors that can replicate in yeast.