Type of chromosome analysis that detects abnormalities of specific chromosomes.
a test to determine HER2 status; tags matching DNA, therefore if more than one HER2 is tagged, there has been an increase.
FISH. A laboratory test that measures the amount of amplification of a certain gene in breast cancer cells. The FISH test is sometimes used to determine whether a breast cancer cell has too much of the HER2/neu protein. Results of this test may help determine treatment options.
A laboratory procedure that uses DNA specific probes and can identify whether a sperm cell contains an X or Y chromosome.
A process which vividly paints chromosomes or portions of chromosomes with fluorescent molecules. This technique is useful for identifying chromosomal abnormalities and gene mapping.
A powerful molecular cytogenetics technique that uses a fluorescent-labeled DNA probe to determine the presence or absence of a particular segment of DNA — the BCR-ABL gene in the case of CML. It combines the ability to identify a specific gene or gene region (molecular) with direct visualization of the cells and/or chromosomes under the microscope (cytogenetics). In the FISH test, about 200 of your cells are generally examined. The examined cells are usually from your bone marrow but also can be from your peripheral blood (that is, the blood in your veins). FISH can detect the BCR-ABL gene in CML patients even when your bone marrow shows you are Philadelphia-chromosome negative.
A technique that uses fluorescent molecules to locate the position of a DNA sequence along the chromosome.
A technique utilizing a fluorescent-labeled DNA probe to detect a particular chromosome or gene.
(FISH) A mapping technique that uses fluorescent tags to identify the locations of specific markers on chromosomes.
A technique that can be used for prenatal diagnosis, in which specifically designed fluorescent molecules are used to "light up" particular genes or sections of chromosomes to make them visible under a microscope. The fluorescence makes even small abnormalities in the chromosomes visible.
a laboratory technique used to determine how many copies of a specific segment of DNA are present or absent in a cell.