in molecular genetics, a labelled fragment of cloned DNA or RNA which is used to detect other DNA or RNA sequences.
A nucleic acid sequence that is used to detect its complementary nucleic acid (see "Target") in a cell population.
Single-stranded DNA labeled with radioactive isotopes or tagged in other ways for ease in identification.
Defined fragment of RNA or DNA, radioactively or chemically labeled, used to locate specific nucleic acid sequences by hybridization.
In general, probe refers to any biochemical/nucleic acid/oligo etc. labelled with radioactive isotopes or tagged in other ways for identification. A probe is used to identify or isolate a gene, its product, or a protein. In microarrays, the probe is immobilised in regular arrangement on the substrate.
A small segment of DNA of known origin, manufactured in the laboratory, which is designed to recognise the DNA on specific parts of chromosomes. A coloured stain can be attached to the probe and used to confirm the presence or absence of a particular gene or mutation.
Defined RNA or DNA fragment, radioactively or chemically labeled, that is used to locate specific nucleic acid sequences by hybridization.
Defined nucleic acid (DNA or RNA) that can be used to identify, usually through autoradiography, specific DNA or RNA molecules bearing the complementary sequence. A labeled (radioactive; antigen; enzyme; fluorescent) nucleic acid complementary to the sequence being searched for in a restriction digest, genome library, northern blot or in situ hybridization.
A segment of single stranded nucleic acid used to identify DNA molecules containing the complementary sequence.
A labeled, single-stranded DNA/RNA fragment, which hybridizes with, and thereby detects and locates, complementary sequences among DNA/RNA fragments on, for example, a nitrocellulose filter.
a DNA molecule that includes a sufficient number of nucleotides to specifically hybridize to DNA or RNA that includes identical or closely related sequences of nucleotides
a DNA or RNA compliment to the gene
a DNA sequence, which is labelled
a labeled DNA fragment cloned from the sex chromosomes
a mixture of synthetic oligonucleotides complementary to beta-actin mRNA species from human, mouse, and rat
an isolated DNA or RNA attached to a detectable label or reporter molecule, e
an isolated polynucleotide to which is attached a conventional detectable label or reporter molecule, e
an oligonucleotide that is designed to be complementary to the mRNA of interest so that it can be used to screen a library
a piece of labeled DNA or RNA, or an antibody, used to detect the function of a gene)
a single-stranded nucleotide sequence that will hybridize with a certain piece of DNA
a specially labelled piece of nucleic acid that results in visualization of the desired gene expression pattern in the tissue section
A labelled molecule which will recognise and bind to a specific target molecule, thus allowing detection of the target. DNA probes are used to locate and quantitate DNA (or RNA) of complementary sequence. Antibody probes may also be used in aspects of recombinant DNA work, e.g. screening an expression library. The label may be radioactive (32P), biotin or digoxygenin (DIG).
A fragment of DNA, usually labeled with radioactive 32P, that detects homologous sequences on southern blots.
A specific, pre-fabricated sequence of DNA or RNA, labeled by one of several methods, used to detect the presence of a complimentary sequence by binding (hybridizing) to it Related Terms: FISH ; Southern blot ; mutation analysis ; restriction fragment length polymorphism analysis
A specific DNA sequence, radioactively or fluorescently labelled, used with hybridisation techniques to detect complementary sequences in a sample of genetic material. See also Complementary DNA.
A nucleic acid molecule that can be used to detect, by complementary base pairing, another nucleic acid molecule that has a complementary or homologous sequence.
Labeled piece of DNA used to detect the presence or absence of a product.
A labeled segment of DNA that is used to bind to and identify a gene or mRNA transcript.
(1) In surgery, a probe is a slender flexible rod with a blunt end used to explore, for example, an opening to see where it goes. (2) In molecular genetics, a probe is a labeled bit of DNA or RNA used to find its complementary sequence or locate a particular clone like homing in on a needle in a haystack. See the entire definition of Probe
Français] A short DNA fragment used to locate a specific sequence of DNA from a chromosome or genome.
A DNA (or RNA) fragment which has been labelled (usually with radioactivity) and used in a hybridisation assay to identify related DNA (or RNA) sequences.
a cloned gene or fragment of a cloned gene which can be made radioactive and used to detect homologous DNA.
A DNA or protein sequence used as a query in a database search.
A small segment of DNA of known origin, designed to recognise complementary DNA on specific parts of chromosomes. The probe can be labelled with a coloured stain and used to confirm the presence or absence of the target material or to identify unknown chromosomal material.
A 25-mer oligonucleotide designed to be complementary to a reference sequence. The probe sequence that is complementary to the sequence to be hybridized.
a portion of single-stranded nucleic acid (DNA or RNA) labeled isotopically or nonisotopically and used to hybridize to specific nucleic acids sequences.
A component of a detection system that must come into contact with product before product can be declared or measured.
a radioactive DNA or RNA molecule used in DNA-RNA or DNA-DNA hybridization trials.
Single-stranded DNA or RNA molecule of specific base sequence, either radioactively or fluorescently labeled, that is used to identify the complementary nucleotide sequence by hybridization to the DNA fragment or gene of interest.
in a microarray experiment, the solution of labeled DNA that is hybridized with the array. For comparative transcription studies, two cDNA probes are prepared from the total mRNA of two different kinds of cells and labeled with two different reporters.
A DNA strand that is used to stain DNA fragments after electrophoresis
Any biochemical agent that is labelled or tagged in some way so that it can be used to identify or isolate a gene, RNA, or protein. Typically refers to the immobilized specified nucleic acid in a detection system.
A scan carried out to discover if a machine has an unpatched vulnerability or is infected with Malware which opens a backdoor. These are detected by both firewalls and IDS / IPS.
A fragment of DNA that will hybridise to another complementary sequence of DNA
Single- stranded DNA or RNA molecules of specific base sequence, labeled either radioactively or immunologically, that are used to detect the complementary base sequence by hybridization.
A single-stranded DNA or RNA molecule with a specific base sequence, labeled either radioactively or immunologically, that is used to detect the complementary base sequence by hybridization.
A length of single-stranded DNA that matches part of a gene that has already been identified. If the DNA probe is made from a mutated gene, it can be used to determine whether someone has that genetic defect. The probe will bind to complementary parts of the patient's gene.
In the context of the immunoblotting experiments, the probe is a molecule that specifically binds to the protein that the investigator is trying to detect. In the Western Blotting experiment, the probe is an antibody raised against the protein of interest.
Defines a nucleic acid segment that can be used to identify specific DNA molecules bearing the complementary sequence, usually through autoradiography.
specific sequence of DNA or RNA, known and labelled with a radioactive substance, used to detect a complementary sequence of DNA or RNA.
Short segment of DNA that is tagged with a radioactive or chemical tracer and is then used to detect the presence of a particular DNA sequence through hybridization to its complementary sequence.
A radiolabeled or fluorescent oligonucleotide used to locate complementary sequences in a hybridization experiment.
A radioactive strand of DNA often used to find particular sequences in a Southern Blot
A specific sequence of DNA or RNA used to detect complementary sequences by hybridization. ( 10)
In Quantitative PCR, single-stranded DNA molecules of specific base sequence, which are used to detect the complementary base sequence.
a specific sequence of single-stranded DNA, typically labeled with a radioactive atom, which is designed to bind to, and thereby single out, a particular segment of DNA.