This is IgG and IgM antibodies directed against negatively charged phospholipids. It is associated with increased risk of thrombotic episode.
A type of antiphospholipid antibody that is detected through blood clotting tests, especially the activated partial thromboplastin time (aPTT). This autoantibody is associated with an increased risk for blood clots.
An antibody first noted in the disease systemic lupus erythematosus or "lupus", that has the ability to stop blood clotting. A cause of recurrent miscarriages. Closely related to a family of anti-phospholipid antibodies, especially anticardiolipin antibody. Also called the lupus inhibitor.
A type of antiphospholipid antibody. Contrary to what the name sounds like, LA antibodies are only loosely associated with Systemic Lupus Erythematosis, the disease. Having LA antibodies does not mean that you have lupus, although it can explain your miscarriages.
Lupus anticoagulant is an autoimmune disorder caused by antibodies that bind to phospholipids and proteins associated with the cell membrane. This antibody has the peculiar nature of causing a delay in coagulation in laboratory tests (the partial thromboplastin time) while clinically predisposing for thrombosis. It is also known as lupus antibody, LA and lupus inhibitor.