Definitions for "Telomere"
Related Terms:
Telomeres, Telomerase, Repetitive dna, Homologous recombination, Yeast artificial chromosome, Replicon, Shotgun sequencing, Operator, Yac , Genomic dna, Restriction fragment, Insertion, Transposase, Promoter, Klenow fragment, Cloning vector, Expression vector, Exons, Pseudogene, Plasmid, Rdna, Cosmid, Homeobox, Bacterial artificial chromosome, Origin of replication, Restriction fragment length polymorphism, Bac, Restriction enzymes, Transposon, Restriction site, Pseudogenes, Restriction enzyme, Chromosome, Tata box, Rflp, Recombinant dna, Okazaki fragment, Recombinant dna technology, Gene cloning, Molecular marker, Dna sequence, Plasmids, Polymerase chain reaction, Recombination, Cpg island, Genome, Homeotic gene, Episome, Intron, Sequencer
End region of a eukaryotic chromosome containing characteristic telomeric (TEL) sequences that are replicated by a special process, thereby counteracting the tendency of a chromosome to be shortened during each round of replication. ( Figure 12-13)
End of a chromosome, associated with a characteristic DNA sequence that is replicated in a special way. Counteracts the tendency of the chromosome otherwise to shorten with each round of replication. (From Greek telos, end.)
One of the ends of each of the four “arms” of a chromosome.
Refers to the end of each chromosome arm distal to the centromere. It consists of special DNA elements (repeats) that are replicated by a special mechanism to help avoid shortening the chromosome ends. The enzyme responsible for this feature is called "telomerase".
A region at the end of each chromosome, consisting of a repeated coding sequences that does not encode for protein. Telomeres aid DNA replication, which cannot proceed once this region has been worn away.
A cap structure at the ends of chromosomes consisting of short repeated sequences with strand asymmetry in GC content, resulting in one G-rich strand and one C-rich strand.
Terminal region of chromosomes characterized by repeated DNA sequences.
The terminal part of a linear chromosome. Replication of the ends of linear DNA molecules requires specialized enzymes or structures. Often the telomers have a DNA sequence with a single-stranded end that can fold into a hairpin structure.
The end of a chromosome. search for Telomere
The most distal portion of a chromosome arm. Telomeres contain a 10-15 kb sequence composed of tandem repeats of a 6 base pair DNA sequence. These sequences appear to be important in protecting the ends of chromosomes from degradation.
either (free) end of a eukaryotic chromosome; "telomeres act as caps to keep the sticky ends of chromosomes from randomly clumping together"
a molecular cap on the end of each chromosome that protects it from damage and also functions in some way as a facilitator for cell division
a region at the end of a chromosome that aids in replication of chromosome ends
a repeating DNA sequence (TTAGGG) at the end of the body's chromosomes
a sequence of genetic information that provides a tag to prevent chromosomes from sticking or mixing with each other during replication
a "tail" at the end of every chromosome (a strand of DNA) that shortens every time the chromosome replicates and divides
The terminal part of a eukaryotic chromosome, consisting of a few hundred base pairs with a defined structure. Telomeres are important for maintaining chromosomal structure and stability, as they permit replication of the ends of the linear DNA molecule.
The region at each end of a chromosome; important for protecting DNA-encoded genetic information through successive generations of cells.
is the end of eukaryotic chromosomes that consist of simple, short repeated sequences that are species specific (Russell, 2002).
DNA sequences found at the end of chromosomes that are necessary to prevent chromosome shortening and degradation
The ends of chromosomes that are normally slightly shortened after each round of cell division. Telomeres are thought to help stabilize chromosomes, and when they become too short after many cell divisions, the cell is no longer able to divide.
TELL-o-meer A chromosome tip. 175
Terminal portion of chromosome involved in chromosomal stability which shortens with each cell division. Implicated in aging and cancer.
The natural distal end of a chromosome. Contain some form of simple repeating sequence, usually with a single stranded distal end that may form a hairpin.
The terminal or end segment of each chromosome arm.
a complex of repetitive DNA sequences that cap the ends of chromosomes. Telomeres play a role in cellular replication via the telomerase enzyme, which helps determine whether cells are able to replicate. Telomeres shorten each time a cell divides, and signal cell senescence (loss of function) when they reach a critical length.
end of a chromosome. Each telomere consists of thousands of copies of the same DNA sequence, repeated again and again. Telomeres become shorter each time a cell divides; when one or more telomeres reaches a minimum length, cell division stops. This mechanism limits the number of times a cell can divide.
The segment at the end of each chromosome arm which consists of a series of repeated DNA sequences that regulate chromosomal replication at each cell division. Some of the telomere is lost each time a cell divides, and eventually, when the telomere is gone, the cell dies.
(TEE-lo-meer) A repetitive segment of DNA at the ends of eukaryotic chromosomes. Telomeres do not contain genes and, in the absence of telomerase, they shorten with each cell division.
The ends of chromosomes. These specialized structures are involved in the replication and stability of linear DNA molecules. See DNA replication.
End portion of chromosome
a series of repeated DNA sequences located at the end of a chromosome. Telomeres serve to assure that a chromosome is replicated properly each time a cell divides. Each time a cell divides, some of the telomere is lost in the process. Eventually little or no telomere remains, and the cell dies.
The end of a chromosome. Telomeres contain repeated DNA sequences and are associated with the replication and stability of the chromosome.
The end of a chromosome. This specialized structure is involved in the replication and stability of linear DNA molecules.
The structures at both ends of a chromosome, made up of the last several thousand DNA bases, as well as proteins which are bound to them. Where the rest of the chromosome contains genes, or coding sequences for proteins, the telomeres are gene-free regions. Unlike the rest of the chromosome, the sequence of DNA bases in the telomeres is invariant and repetitive. In humans, the repeating sequence is TTAGGG (thymine, thymine, adenine, guanine, guanine, guanine)
The free end of a chromosome.
Tip of chromosome.
regions at the end of chromosomes. Shortening of the telomeres is thought to be associated with cellular aging. The enzyme that maintains the telomere is called telomerase. Introducing this gene into a cell can extend the cells lifespan.
A telomere is a region of highly repetitive DNA at the end of a linear chromosome that functions as a disposable buffer. Every time linear eukaryotic chromosomes are replicated during late S-phase the DNA polymerase complex is incapable of replicating all the way to the end of the chromosome; if it were not for telomeres, this would quickly result in the loss of vital genetic information, which is needed to sustain a cell's activities. Every time a cell with linear genes divides, it will lose a small piece of one of its strands of DNA.
even though certain portions of the genome - namely the centromeres and telomeres, which are the highly repetitive regions at the center ... (IOCeleraGenome) Telômero O cientista russo A.M. Olovnikov propõe uma teoria de envelhecimento associada à perda de telômeros ... (POUniverRS)