(tee´ lo merz) [Gr. telos: end] • Repeated DNA sequences at the ends of eukaryotic chromosomes. Telophase (tee´ lo phase) [Gr. telos: end] • The final phase of mitosis or meiosis during which chromosomes became diffuse, nuclear envelopes reform, and nucleoli begin to reappear in the daughter nuclei.
tips of the chromosomes that contain nucleotides that complete each cycle of DNA replication; composed of a specific arrangement of 6nucleotides (TTAGGG) repeated a few hundred to a thousand times.
Special DNA sequences at the ends of each chromosome that grow shorter each time a cell divides. Telomeres count the number of cell divisions, and when it shortens to a certain length, the cell will stop dividing (senescence) and eventually die.
the long end sequences of a DNA strand occurring at the tip of the chromosomes that appear to be associated with replicative senescence.
A series of repeated DNA sequences at the 5´ end of a chromosome that ensure correct chromosome replication during cell division; each time a cell divides, some of the telomeres are lost in the process, eventually leaving little or no telomeres and resulting in cell death.
The simple repeated sequences at the ends of chromosomes that protect them from loss of coding sequence during replication. In the absence of telomerase, telomeres become progressively shorter with each cell division, and this shortening is the major cause of senescence of cells and culture. http://zoom.nap.edu/nap-cgi/rezoom.cgi?isbn=0309084393&page=168
Repeated DNA sequences found at the ends of chromosomes; telomeres shorten each time a cell divides.
specialized DNA-protein structures that cap DNA (chormosome) ends. Telomeric structures are crucial for maintaining DNA integrity and rpeserving genome stability. Dysfunctional telomeres lead to genomic instability. Genomic instability is a hallmark of cancer and has also been proposed to contribute to aging.
The ends of chromosomes. These specialized structures are involved in the replication and stability of DNA molecules.
The DNA–protein structure that stabilizes the ends of linear chromosomes and protects them from degradation or fusion. In vertebrates, telomeres are composed of several-kilobase pairs of the sequence TTTAGGG and several associated proteins.
"Caps" (made of repeated DNA sequences) found at the ends of chromosomes that protect the ends of the chromosomes from degradation. The telomeres on a chromosome shorten with each round of cell replication. Telomere shortening has been suggested to be a "clock" that regulates how many times an individual cell can divide (that is, when the telomeres of the chromosomes in a cell shorten past a particular point, the cell can no longer divide).
