The lowest concentration of a substance that can be determined to be significantly different from zero.
the lower boundary of an assay (e.g., a viral load test). The limit of detection is the level below which a test cannot measure the presence of a component (e.g., HIV RNA).
"Detection limit is the lowest concentration of analyte in a sample that can be detected, but not necessarily quantitated, under the stated experimental conditions".
The lowest concentration of an analyte that can be detected reliably (present or absent) in a particular sample. Exact definitions vary.
Lowest concentration of a pesticide residue in a defined matrix where positive identification can be achieved using a specified method.
The minimum amount of the characteristic property being measured that can be detected with reasonable certainty by the analytical procedure being used under specific measuring conditions. If the conditions change, the limit of detection will also change, even if the analytical procedure remains the same. See also lower limit of detection.
The minimum concentration of an analyte that, in a given matrix and with a specific method, has a 99% probability of being identified, qualitatively or quantitatively measured, and reported to be greater than zero.
The lowest concentration of an analyte that the bioanalytical procedure can reliably differentiate from background noise.
Lowest level of a material that can be detected by technique - typically signal is three times baseline noise.
refers to the SENSITIVITY of a quantitative diagnostic test, such as the VIRAL LOAD ASSAY. The limit of detection is the level below which the test can no longer accurately measure the amount of a substance, such as HIV RNA. If a person has an "undetectable" viral load, it does not mean that HIV is no longer present, but rather, that the test is not sensitive enough to measure the amount (see also RESERVOIR). Also called the limit of quantification.
The minimum concentration of a substance being analyzed test that has a 99 percent probability of being identified.
