Proteins that bind to DNA and regulate gene expression.
TF) General term for any protein, other than RNA polymerase, required to initiate or regulate transcription in eukaryotic cells. General factors, required for transcription of all genes, participate in formation of the transcription-initiation complex near the start site. Specific factors stimulate (or repress) transcription of particular genes by binding to their regulatory sequences.
A protein that activates initiation of eukaryotic transcription.
factors that bind to regulatory elements in DNA known as promoters and enhancers, that stimulate (or inhibit) gene transcription and the formation of mRNA through direct interactions with DNA.
Term loosely applied to any protein required to initiate or regulate transcription in eucaryotes. Includes both gene regulatory proteins as well as the general transcription factors.
A regulatory protein that binds to DNA and stimulates transcription of specific genes. transduction trans, across + ducere, to lead] The transfer of genetic material (DNA) from one cell to another by a virus.
A term used to describe any protein that participates in initiating transcription. Transcription factors bind either to DNA or to other proteins that bind DNA.
a factor (protein or protein with steroid) that binds to DNA to alter gene expression, usually to activate. (eg steroid hormone+receptor, Retinoic acid+Receptor, Hox, Pax, Lim, Nkx-2.2). (More? Molecular Notes)
a protein involved in the expression of a gene
a protein that binds to specific locations in DNA and regulates, either enhancing or suppressing, the transcription of the DNA into RNA
a protein that can combine with other proteins (in this case, beta-catenin) so that it can turn certain genes in the cell's DNA on or off
a protein which regulates the process of transcription
(synonym: zinc finger protein) A protein that aids in the activation and regulation of transcription, in which messenger RNA is synthesized from the DNA template; zinc finger proteins are one type of transcription factor
tranz-SCRIPT-shun fac-tor A protein that turns on and off different genes in a particular cell. 327
A protein whose function is to control the act of transcription.
A protein which is involved in the transcription of genes. These usually bind to DNA as part of their function (but not necessarily). A transcription factor may be general (i.e. acting on many or all genes in all tissues), or tissue-specific (i.e. present only in a particular cell type, and activating the genes restricted to that cell type). Its activity may be constitutive, or may depend on the presence of some stimulus; for example, the glucocorticoid receptor is a transcription factor which is active only when glucocorticoids are present.
A protein that regulates the transcription of genes.
A molecule, typically a protein, which binds to DNA binding sites with some regulatory role in transcription. The binding (or unbinding) of a transcription factor from a promoter eventually leads to a change of transcription activity in the gene controlled by that promoter.
A protein that binds to regulatory regions and controls gene expression.
A protein that binds to DNA and plays a role in the regulation of gene expression by promoting transcription.
A DNA-binding protein required for the activation and regulation of expression of a gene.
A protein that binds to a cis-regulatory element (for example, an enhancer) and thereby, directly or indirectly, affects the initiation of transcription.
Generally a protein that functions to initiate, enhance, or inhibit the transcription of a gene. Transcription factors can regulate the formation of a specific protein encoded by a gene.
a protein which binds to DNA activating (usually) gene expression. There are many different ways and forms that this activation can take place, but most transcription factors fall into specific classes (eg zinc fingers, helix loop helix).
While this is an accurate description, it requires some prior knowledge of complex DNA transcription processes. A more simplistic definition can be found under the term promoter.In molecular biology, a transcription factor is a protein that regulates the binding of RNA polymerase and the initiation of transcription. A transcription factor binds upstream to either enhance or repress transcription of a gene by assisting or blocking RNA polymerase binding.