AST is an enzyme found mostly in the heart and liver. When liver or muscle cells are injured, they release AST into the blood. It also may be released from red blood cells if those cells are damaged when blood is being drawn.
Aspartate aminotransferase, an enzyme normally present in liver and heart cells. AST is released into blood when the liver or heart is damaged. The blood AST levels are thus elevated with liver damage (for example, from viral hepatitis) or with an insult to the heart (for example, from a heart attack). Some medications can also raise AST levels. AST is also known as serum glutamic oxaloacetic transaminase (SGOT). Androgen suppression therapy. See: Androgen suppression.
Aspartate aminotransferase - a protein which, when found in the blood in elevated quantities, generally indicates liver damage (although less specific for liver damage than ALT).